Active-ingredient Dossier

Cladribine

Active-ingredient Dossier for Cladribine (purine nucleoside antimetabolite). Australian brands, products, PBS listings, PBAC outcomes — compiled by…

What is

Cladribine Cladribine is a purine nucleoside antimetabolite.

Australian brands containing

Cladribine — LEUSTATIN — MAVENCLAD — LITAK — CLADRITAB

Therapeutic areas

Cladribine is registered in two therapeutic areas: neurology, with two brands, and oncology, with two brands.

Sponsor landscape

Three sponsors market cladribine-containing products in Australia: Merck Healthcare, Atnahs Pharma, and Viatris.

PBS and regulatory activity

Two brands containing cladribine have PBS-listed items, with the latest PBS schedule date being 1 May 2026. In the 2023–24 financial year, government expenditure on cladribine products was $76,307,661 across 4,725 scripts. Three brands have PBAC outcomes on record, with the latest PBAC review occurring on 1 November 2023. One brand has an AusPAR on record, dated 5 December 2017.