Active-ingredient Dossier

Denosumab

Active-ingredient Dossier for Denosumab (monoclonal antibody). Australian brands, products, PBS listings, PBAC outcomes — compiled by arcimedes.

What is

Denosumab Denosumab is a monoclonal antibody.

Australian brands containing

Denosumab — JUBBONTI — WYOST — XGEVA — DENOLIA — DESKELTIA — DEXEVA — DOSTIVA — PROLIA — OSPOMYV — XBORSO — CORORA — GANVADO

Therapeutic areas

Denosumab is registered in oncology (14 brands) and endocrinology (3 brands).

Sponsor landscape

Denosumab is marketed by five sponsors: Amgen, Accord Healthcare, Sandoz, Celltrion Healthcare, and Samsung Bioepis AU.

PBS and regulatory activity

Three brands containing denosumab have PBS-listed items, with the latest PBS schedule date of 1 May 2026. In the 2024–25 fiscal year, PBS expenditure on denosumab was approximately $307.4 million across 1.22 million scripts. The latest PBAC outcome was recorded on 1 November 2025, and the latest AusPAR was issued on 26 March 2026. Three brands have PBAC outcomes on record, and ten brands have AusPARs on record.