Product Dossier

SYMTUZA

Product Dossier for SYMTUZA (cobicistat, darunavir, emtricitabine, tenofovir alafenamide, Janssen-Cilag). ARTG record, PBS listing, PBAC outcomes —…

What it is

SYMTUZA is a film-coated tablet containing 800 mg darunavir, 150 mg cobicistat, 200 mg emtricitabine and 10 mg tenofovir alafenamide.

Approved indications

— Human immunodeficiency virus (HIV) infection.

Key safety warnings

The product information documents provided do not contain safety information specific to SYMTUZA. Prescribers should consult the current product information for SYMTUZA and relevant HIV treatment guidelines for comprehensive safety advice.

PBS listing

SYMTUZA 800/150/200/10 mg is listed on the PBS with an Authority Required (Streamlined) restriction as part of the Highly Specialised Drugs Program — Community Access, on a weighted cost minimisation basis with alternative treatments.

Regulatory history

SYMTUZA was registered on the Australian Register of Therapeutic Goods on 22 November 2019. In November 2019, the Pharmaceutical Benefits Scheme Advice Committee recommended it for listing for the treatment of human immunodeficiency virus (HIV) infection.