MatriDerm Flex Dermal Matrix - Dermal tissue reconstructive material, animal-derived

Intended purpose

MatriDerm is used in combination with autologous split-thickness skin grafts for the reconstruction of deep dermal defects and full-thickness skin wounds in plastic reconstructive surgery and in the surgical treatment of burns, trauma and dermatological diseases. It is also used in the treatment of graft requiring poorly healing wounds (e.g. chronic wounds). Additionally, MatriDerm can be used for the reconstruction of mucosal defects. The aim of treatment is to construct a neodermis, in order to improve the quality of reconstituted tissue, reduce scarring, prevent wound contraction and restore functionality. MatriDerm can also be used under intact skin for the temporary separation of tissues, thereby preventing adherence, especially of tendons and their surrounding connective tissue, after injuries or surgical procedures.

Functional description

MatriDerm is a resorbable dermal scaffold applied to a wound bed to support dermal regeneration. Used with a split-thickness skin graft, it promotes cell infiltration, angiogenesis, neodermis formation, and graft integration while modulating scar formation. The matrix provides temporary tissue separation and is gradually resorbed as host tissue remodels.